Lactobionic Acid-Benzoic Acid（CAS 96-82-2）

Lactobionic Acid-Benzoic Acid（CAS 96-82-2）

• Lactobionic Acid (LBA) is a next-generation polyhydroxy acid (PHA), often referred to as the "third generation fruit acid," derived from the oxidation of lactose, a natural milk sugar. Structurally, it consists of one molecule of galactose linked to one molecule of gluconic acid, giving it a large molecular size with eight hydroxyl groups — significantly larger than traditional AHAs like glycolic acid and lactic acid.

• This larger molecular size means lactobionic acid penetrates the skin more slowly and gently, working primarily on the outermost layers of the stratum corneum, resulting in far less irritation than first-generation AHAs while still delivering effective exfoliation.

• As a multifunctional skincare active, lactobionic acid offers multiple benefits: it provides gentle keratolytic exfoliation by loosening the bonds between dead skin cells; it acts as a powerful humectant with its eight hydroxyl groups attracting and holding water molecules for deep hydration; it exhibits antioxidant and metal-chelating properties, inhibiting matrix metalloproteinases (MMPs) that break down collagen; it supports collagen synthesis and improves skin elasticity; it helps cleanse pores and reduce blackheads; and it brightens skin tone and improves texture.

• With its excellent safety profile and minimal irritation potential, lactobionic acid is particularly suitable for sensitive skin, rosacea-prone skin, and post-procedure skin that cannot tolerate stronger AHAs. It is widely used in gentle exfoliants, pore-cleansing products, hydrating serums, anti-aging treatments, and sensitive skin care formulations.

Key Benefits

• Third generation PHA, significantly gentler than AHAs, large molecule slow penetration, minimal irritation

• Superior hydration with 8 hydroxyl groups, powerful humectant, deep long-lasting moisture

• Gentle exfoliation, loosens dead skin cell bonds, promotes natural shedding, improves texture

• Antioxidant & MMP inhibition, protects collagen from degradation, anti-aging benefits

• Stimulates collagen synthesis, improves skin elasticity, reduces fine lines and wrinkles

• Pore cleansing & blackhead removal, "pore vacuum" effect, reduces pore congestion

• Bi-directional keratin regulation, doesn't over-strip, supports healthy barrier function

• Skin brightening, improves dullness and roughness, reveals radiant glowing skin

• Metal chelation, stabilizes formulations, enhances preservative efficacy

Applications

• Gentle exfoliating products, peeling serums: Recommended dosage 2%–6%

• Pore cleansing products, blackhead removing solutions: Recommended dosage 2%–5%

• Hydrating serums, creams & lotions: Recommended dosage 1%–5%

• Anti-aging serums, anti-wrinkle creams: Recommended dosage 2%–5%

• Sensitive skin repair products, barrier repair creams: Recommended dosage 1%–3%

• Brightening products, glow serums: Recommended dosage 2%–5%

• Toners, essences & lotions: Recommended dosage 1%–4%

• Facial masks (sheet masks, wash-off masks): Recommended dosage 2%–5%

• Body lotions & moisturizers: Recommended dosage 1%–3%

• Hair & scalp care (anti-dandruff, oil control): Recommended dosage 0.5%–2%

Certificate Of Analysis (COA)

Frequently Asked Questions (FAQ) & Document Request Frequently Asked Questions (FAQ) & Document Request

Q1: What generation of fruit acid is lactobionic acid? What is the difference from first-generation AHAs like glycolic acid and lactic acid?

A: Lactobionic acid is classified as a third-generation fruit acid, also known as a polyhydroxy acid (PHA). The key difference from first-generation AHAs (glycolic acid, lactic acid) lies in molecular size, penetration rate, irritation potential, and additional benefits. First-generation AHAs have small molecular sizes (glycolic acid is the smallest AHA), allowing them to penetrate the skin quickly and deeply — this makes them highly effective for exfoliation but also more likely to cause irritation, redness, and sensitivity, especially at higher concentrations. Lactobionic acid, as a PHA, has a much larger molecular structure (molecular weight 358.3 vs. glycolic acid's 76), so it penetrates more slowly and stays primarily in the outermost layers of the stratum corneum. This results in significantly gentler exfoliation with minimal irritation. Additionally, lactobionic acid offers benefits that AHAs don't: it has 8 hydroxyl groups providing superior hydration (AHAs can be drying), it has antioxidant and metal-chelating properties (protecting collagen from MMP degradation), and it supports skin barrier repair rather than potentially compromising it. In summary: AHAs = stronger, faster exfoliation but more irritation and potential drying; Lactobionic acid (PHA) = gentler exfoliation, better hydration, antioxidant protection, barrier support, suitable for sensitive skin.

Q2: Is lactobionic acid really gentler than traditional fruit acids? Can people with sensitive skin use it?

A: Yes, lactobionic acid is widely recognized as significantly gentler than traditional AHAs like glycolic acid, and it is generally well-tolerated by most sensitive skin types. The gentleness comes from its large molecular size — at 358.3 Daltons, it's nearly 5 times larger than glycolic acid (76 Daltons), so it cannot penetrate deeply or quickly into the skin. Instead, it works gradually on the skin's surface, gently loosening dead skin cells without causing the inflammation or barrier disruption that stronger acids can trigger. Clinical studies and practical formulation experience have shown that lactobionic acid causes minimal to no stinging, burning, or redness, even at effective concentrations. It is often recommended for: sensitive skin that cannot tolerate glycolic acid or other AHAs; rosacea-prone skin; post-procedure skin (after laser, chemical peel, or microdermabrasion) that needs gentle exfoliation without irritation; and dry or dehydrated skin that would be worsened by drying AHAs. However, as with any active ingredient, individual sensitivity can vary — we always recommend patch testing before full-face use, especially for extremely sensitive skin. Overall, lactobionic acid is considered one of the gentlest exfoliating acids available in skincare.

Q3: How is lactobionic acid's moisturizing effect? How does it compare to hyaluronic acid and glycerin?

A: Lactobionic acid has excellent moisturizing properties, thanks to its eight hydroxyl groups that can attract and bind water molecules. It is classified as a humectant — meaning it draws moisture from the environment and from deeper skin layers to the surface. Compared to other common humectants: Glycerin is a small-molecule humectant with 3 hydroxyl groups, widely used and very effective but can feel sticky at high concentrations. Hyaluronic acid (HA) is a large polysaccharide that can hold 1000x its weight in water, primarily working on the skin surface (especially high molecular weight HA) to create a plumping, hydrating film. Lactobionic acid falls somewhere in between — it has more hydroxyl groups than glycerin (8 vs. 3), giving it strong water-binding capacity, and while it doesn't hold as much water per gram as HA, it has the added advantage of being able to penetrate slightly into the stratum corneum and provide exfoliating and antioxidant benefits at the same time. The unique advantage of lactobionic acid is that it's a multi-functional ingredient — it provides hydration AND gentle exfoliation AND antioxidant protection AND barrier support, all in one. Many formulators combine lactobionic acid with hyaluronic acid and/or glycerin for synergistic hydration — the HA provides surface plumping, the glycerin provides deep humectancy, and the lactobionic acid provides gentle exfoliation to improve texture while adding its own hydration contribution.

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