Cosmetic Grade Plant-derived Squalene(CAS 111-02-4)
Product Name: Squalene
INCI Name: Squalene
Common Name: Spinacene
CAS Number: 111-02-4
Molecular Formula: C₃₀H₅₀
Molecular Weight: 410.71
Product Purity: ≥99.2%
Appearance: Colorless to pale yellow clear oily liquid, slight natural plant odor, no fishy smell
Shelf Life: 24 months under sealed cool, dry and dark storage
Plant-derived squalene, cosmetic grade squalene oil, skin sebum matching emollient, natural skin barrier repair oil, vegan squalene, anti-oxidation cosmetic oil, bulk squalene supplier, moisturizing skincare raw material
Cosmetic Grade Plant-derived Squalene(CAS 111-02-4)
Squalene is a natural unsaturated lipid that is highly homologous with human skin sebum, accounting for about 10%-16% of human epidermal sebum. This batch adopts pure amaranth seed plant extraction technology, completely replacing traditional shark liver-derived squalene to meet clean beauty and vegan market demands. Different from saturated squalane, squalene owns excellent free radical scavenging antioxidant activity, can reduce skin oxidative aging caused by UV radiation and external stimulation. It has outstanding skin affinity, can quickly penetrate into bottom skin without heavy oily film, repair fragile barrier, relieve dryness, tightness and sensitivity. It is a core natural emollient essential for barrier repair, anti-oxidation and daily moisturizing skincare formulas.

Key Benefits
• Deeply replenish missing sebum, repair damaged skin barrier from the source
• Promote transdermal absorption of other oil-soluble active ingredients to improve formula efficacy
• Light and non-greasy skin feel, good spreadability without sticky oil film on skin surface
• Relieve skin dryness, tightness, peeling and seasonal sensitivity effectively
• Good compatibility with all cosmetic oil phases, easy formula deployment without delamination
• Improve hair dryness and split ends, moisturize scalp without clogging hair follicles
• Nitrogen-filled packaging effectively slows down oil oxidation and extends formula shelf life
Applications
• Pure plant facial repair oil: Recommended dosage 20%-100%
• Barrier repair cream and soothing lotion: Recommended dosage 2%-8%
• Anti-photoaging antioxidant serum: Recommended dosage 3%-6%
• Physical & chemical sunscreen oil phase system: Recommended dosage 1%-5%
• Post-sun repair skincare products to relieve UV-induced skin damage
• Dry and sensitive skin daily moisturizing skincare series
• Leave-in hair oil and scalp care essence for dry damaged hair
• Makeup base oil to improve foundation fit and prevent powder floating
• Compound emollient formula matched with squalane, caprylic/capric triglyceride
Certificate Of Analysis (COA)
Test Item | Standard Requirement | Test Result | Test Method |
Appearance | Colorless to pale yellow clear oil liquid, slight plant odor | Complied | Visual & Olfactory Inspection |
Squalene Purity (GC) | ≥99.2% | 99.57% | Gas Chromatography |
Acid Value (mgKOH/g) | ≤0.1 | 0.03 | GB/T 5530 |
Peroxide Value (meq/kg) | ≤5.0 | 2.14 | GB/T 5538 |
Iodine Value (g/100g) | 360 - 380 | 371.6 | GB/T 5532 |
Relative Density (20℃) | 0.854 - 0.862 | 0.858 | Density Bottle Method |
Refractive Index (20℃) | 1.494 - 1.498 | 1.496 | Abbe Refractometer |
Moisture Content | ≤0.05% | 0.02% | Karl Fischer Method |
Heavy Metal Lead (Pb) | ≤1ppm | <0.5ppm | ICP-MS |
Heavy Metal Arsenic (As) | ≤1ppm | <0.5ppm | ICP-MS |
Total Aerobic Bacteria | ≤10CFU/g | Not Detected | Plate Count Method |
Conclusion | Meet global cosmetic grade squalene standard | Qualified | / |
Frequently Asked Questions (FAQ) & Document Request Frequently Asked Questions (FAQ) & Document Request
Q1: What is the core difference between squalene and squalane for cosmetic formulation?
A: Squalene is unsaturated oil with strong antioxidant activity but slightly poorer oxidation stability; Squalane is saturated hydrogenated oil with better stability and longer shelf life. Formulators usually compound squalene + squalane to balance antioxidant capacity and oxidation resistance, achieving both anti-aging efficacy and stable formula storage.
Q2: Can squalene be directly compounded with retinol and VC anti-aging active ingredients?
A: Yes, it has excellent compatibility with retinol, VC derivatives and other lipophilic anti-aging ingredients. Squalene can relieve retinol irritation, stabilize active structure, and enhance the overall anti-oxidation and anti-aging effect of compound formulas.
Q3: What is the optimal compound ratio of squalene and squalane for daily moisturizing cream?
A: The classic golden ratio is 3% squalene + 3% squalane. This formula balances antioxidant effect and oil stability, brings natural skin sebum-like moisturizing feeling, and greatly prolongs the shelf life of emulsified skincare products.
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