Cosmetic Grade Inositol, Natural Moisturizing Factor（CAS 87-89-8）
Product Name: Inositol (Myo-Inositol)
INCI Name: INOSITOL
Common Name: Vitamin B8, Cyclohexanehexol
CAS Number: 87-89-8
EINECS Number: 201-781-2
Molecular Formula: C₆H₁₂O₆
Molecular Weight: 180.16 g/mol
Product Purity: ≥99.0%
Appearance: White crystalline powder, odorless
Melting Point: 222–227°C
Shelf Life: 24 months under sealed cool, dry and dark storage
Inositol, Myo-Inositol, Vitamin B8, cosmetic grade inositol, natural moisturizing factor, skin barrier repair ingredient, antioxidant skincare ingredient, hair conditioning agent, sensitive skin ingredient, water-soluble vitamin powder
Cosmetic Grade Inositol, Natural Moisturizing Factor（CAS 87-89-8）
Inositol, also known as Myo-Inositol or Vitamin B8, is a naturally occurring sugar alcohol widely found in plants and animal tissues. As a pseudo-vitamin of the B-complex family, it plays essential roles in cell membrane structure, signal transduction, and osmotic regulation. In cosmetics and personal care, inositol is valued for its multifunctional benefits: it acts as a natural moisturizing factor (NMF) that attracts and retains skin moisture, supports skin barrier function to reduce transepidermal water loss, and provides mild antioxidant protection against environmental stressors. Its water-soluble nature and excellent formulation compatibility make it easy to incorporate into a wide range of skincare, haircare, and body care products. Backed by extensive safety assessments including the US FDA CIR review, cosmetic grade inositol is a gentle, versatile ingredient suitable for all skin types, including sensitive and baby skin.
Key Benefits
• Excellent moisturizing performance, acts as natural moisturizing factor (NMF) to lock in hydration
• Strengthens skin barrier function, reduces transepidermal water loss (TEWL)
• Mild antioxidant protection, defends cell membranes against free radical damage
• Participates in cell signaling pathways, supports skin's natural repair mechanisms
• Gentle and non-irritating, suitable for sensitive skin and all skin types
• Effective hair conditioning, reduces static electricity, improves shine and combability
• Osmoprotective effect, helps skin cells maintain hydration under environmental stress
• Excellent water solubility, strong formulation compatibility, easy to incorporate
• Natural origin, can be derived from plant extraction or bio-fermentation
• Brightens complexion, improves dullness, supports even skin tone
Applications
• Moisturizing creams, lotions & serums: Recommended dosage 0.5%–3%
• Sensitive skin repair products, barrier repair creams: Recommended dosage 1%–3%
• Anti-aging serums, anti-wrinkle creams: Recommended dosage 0.5%–2%
• Hair conditioners, hair masks & shampoos: Recommended dosage 0.1%–1%
• Toners, essences & lotions: Recommended dosage 0.5%–2%
• Sunscreen lotions & creams: Recommended dosage 0.5%–2%
• Facial masks (sheet masks, wash-off masks): Recommended dosage 0.5%–2%
• Body lotions & moisturizers: Recommended dosage 0.3%–1%
• Baby care products (baby lotion, diaper cream): Recommended dosage 0.1%–0.5%
• Lip care products (lip balm, lip mask): Recommended dosage 0.5%–1%
Certificate Of Analysis (COA)
Test Item | Standard Requirement | Test Result | Test Method |
Appearance | White crystalline powder, odorless | Complied | Visual & Olfactory Inspection |
Assay (HPLC) | ≥99.0% | 99.62% | High Performance Liquid Chromatography |
Melting Point | 222–227°C | 224.5°C | Capillary Method |
Loss on Drying | ≤0.5% | 0.18% | Gravimetric Method (105°C) |
Residue on Ignition | ≤0.1% | 0.04% | Gravimetric Method |
pH Value (10% solution) | 5.0–7.0 | 5.8 | pH Meter |
Chloride | ≤0.005% | <0.002% | Silver Nitrate Turbidimetry |
Sulfate | ≤0.006% | <0.003% | Barium Chloride Turbidimetry |
Calcium Salt | Negative | Negative | Oxalate Precipitation Test |
Heavy Metal (as Pb) | ≤10 ppm | <2 ppm | ICP-MS |
Arsenic (As) | ≤2 ppm | <0.5 ppm | ICP-MS |
Total Aerobic Bacteria | ≤1000 CFU/g | <100 CFU/g | Plate Count Method |
Mold & Yeast | ≤100 CFU/g | <10 CFU/g | Plate Count Method |
Escherichia Coli | Negative | Not Detected | National Standard Test |
Conclusion | Meet global cosmetic grade inositol standard | Qualified | / |
Frequently Asked Questions (FAQ) & Document Request Frequently Asked Questions (FAQ) & Document Request
Q1: How does inositol's moisturizing effect compare to hyaluronic acid and glycerin?
A: Inositol, hyaluronic acid, and glycerin are all excellent humectants but work at different levels. Glycerin is a small molecule that draws water quickly but can also pull moisture from deeper skin layers in very dry environments. Hyaluronic acid is a large molecule that forms a hydrating film on the skin surface. Inositol works differently — as an osmoprotectant, it penetrates into skin cells and helps them maintain their internal hydration balance, supporting long-term barrier health rather than just surface hydration. It is often used in combination with hyaluronic acid and glycerin for multi-level moisturization: surface film (HA), immediate hydration (glycerin), and cellular-level moisture balance (inositol).
Q2: Can inositol really repair the skin barrier? Is there research data to support this?
A: Yes, there is scientific evidence supporting inositol's barrier repair benefits. Clinical studies have shown that topical application of 2% inositol can improve skin barrier function by reducing transepidermal water loss (TEWL) and enhancing ceramide synthesis. Inositol is a precursor to phosphatidylinositol, a key component of cell membranes and signaling lipids that regulate barrier homeostasis. It also supports the skin's natural lipid production and helps maintain the structural integrity of the stratum corneum. Multiple published studies in dermatology journals have demonstrated its efficacy in improving barrier function, especially in sensitive and dry skin conditions.
Q3: How stable is inositol? Does it easily lose activity in formulations?
A: Inositol has excellent stability. As a saturated cyclic polyol with no double bonds or reactive groups, it is resistant to oxidation and thermal degradation under normal cosmetic processing conditions. It remains stable across a wide pH range (3–10) and does not easily react with other formulation ingredients. However, it may slowly degrade under very high heat (above 150°C) or strongly alkaline conditions (pH > 10) for extended periods. In typical cosmetic formulations stored under normal conditions, inositol maintains its activity for the full product shelf life. It is also compatible with common preservative systems and does not interfere with product preservation.
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