Ethylhexylglycerin-Multi Functional Preservative Enhancer and Skin Conditioner
Product Name: Ethylhexylglycerin
Chemical Name: 3-[(2-Ethylhexyl)oxy]-1,2-propanediol, Octoxyglycerin
CAS Number: 70445-33-9
INCI Name: Ethylhexylglycerin
Purity: ≥99.0% (Cosmetic Grade), ≥99.5% (High-Purity Grade)
Appearance: Colorless to pale yellow, clear, slightly viscous liquid
Molecular Formula: C₁₁H₂₄O₃
Molecular Weight: 204.31 g/mol
Ethylhexylglycerin, Octoxyglycerin, CAS 70445-33-9, preservative booster
Ethylhexylglycerin-Multi Functional Preservative Enhancer and Skin Conditioner(CAS 70445-33-9)
Ethylhexylglycerin (CAS 70445-33-9), also known as Octoxyglycerin, is a versatile multifunctional cosmetic ingredient renowned for its exceptional preservative boosting properties, skin conditioning benefits, and deodorant activity. As an alkyl glyceryl ether derivative, it has become an essential component in modern clean beauty formulations.
Its unique amphiphilic molecular structure allows it to disrupt microbial cell membrane integrity, significantly enhancing the efficacy of traditional preservatives such as Phenoxyethanol, parabens, and organic acids. This synergistic effect enables formulators to reduce total preservative levels by 30-50% while maintaining or improving antimicrobial protection, resulting in milder, more consumer-friendly products.
Beyond preservation, Ethylhexylglycerin functions as an excellent skin conditioner and humectant, improving product spreadability and imparting a silky, non-greasy skin feel. Its deodorant properties, achieved by selectively inhibiting odor-causing bacteria without disrupting beneficial skin flora, make it ideal for deodorants and personal hygiene products.
Our high-purity Ethylhexylglycerin is manufactured through advanced etherification and purification processes, ensuring consistent quality, low odor, and excellent color stability for premium cosmetic applications.

Certificate of Analysis (COA)
Item | Specification | Test Result |
Product Identification | ||
Product Name | Ethylhexylglycerin | Ethylhexylglycerin |
Quality Parameters | ||
Appearance | Clear colorless to pale yellow liquid | Clear colorless liquid |
Odor | Characteristic, mild | Conforms |
Assay (GC) | ≥99.0% | 99.68% |
Color (APHA) | ≤50 | 15 |
Water Content | ≤0.5% | 0.18% |
Refractive Index (20°C) | 1.448-1.452 | 1.4501 |
Specific Gravity (20°C) | 0.958-0.966 | 0.9624 |
pH (1% Dispersion) | 5.0-7.0 | 6.2 |
Acid Value | ≤1.0 mg KOH/g | 0.32 mg KOH/g |
Hydroxyl Value | 530-570 mg KOH/g | 552 mg KOH/g |
Heavy Metals (as Pb) | ≤10 ppm | <5 ppm |
Arsenic (As) | ≤2 ppm | <1 ppm |
Mercury (Hg) | ≤1 ppm | <0.1 ppm |
Cadmium (Cd) | ≤1 ppm | <0.1 ppm |
Residue on Ignition | ≤0.1% | 0.02% |
Microbiological Test | ||
Total Aerobic Count | ≤100 CFU/g | <10 CFU/g |
Yeast & Mold | ≤10 CFU/g | <10 CFU/g |
Conclusion | Qualified | Qualified |
Key Benefits
✅ Powerful Preservative Booster - Enhances preservative efficacy by 2-4x, enabling 30-50% reduction in total preservative usage
✅ Synergistic with Phenoxyethanol - The industry gold standard combination: 0.9% Phenoxyethanol + 0.1% Ethylhexylglycerin delivers superior broad-spectrum protection
✅ Multifunctional Performance - Single ingredient provides preservation boosting, moisturization, skin conditioning, and deodorant activity
✅ Exceptional Skin Mildness - Significantly lower irritation potential vs traditional preservatives, suitable for sensitive skin and baby care
✅ Skin Microbiome Friendly - Selectively targets pathogenic bacteria while preserving beneficial skin flora
✅ Improved Skin Feel - Imparts silky, non-greasy texture and enhances product spreadability
✅ Broad Formulation Compatibility - Stable across pH 3-9, heat-resistant up to 80°C, compatible with all cosmetic ingredients
✅ Clean Beauty Compatible - Paraben-free, formaldehyde-free, and meets global clean label standards
✅ Natural Deodorant Activity - Inhibits odor-causing bacteria without aluminum or harsh antiperspirants
Applications
Cosmetics & Personal Care:
• Skin care: Moisturizers, creams, lotions, serums, toners, masks, eye care products
• Hair care: Shampoos, conditioners, hair treatments, styling products
• Body care: Body washes, shower gels, liquid soaps, body lotions
• Baby care: Baby wipes, diaper creams, gentle cleansers, baby lotions
• Deodorants & antiperspirants: Roll-ons, sticks, sprays, natural deodorants
• Wet wipes: Baby wipes, facial wipes, cleansing wipes, disinfectant wipes
• Makeup: Foundations, concealers, lip products, mascaras
• Sun care: Sunscreens, after-sun products, self-tanners
Frequently Asked Questions (FAQ) & Document Request
Q1: What is the optimal ratio of Ethylhexylglycerin to Phenoxyethanol?
A: The industry-proven golden ratio is 1:9 (0.1% Ethylhexylglycerin + 0.9% Phenoxyethanol). This combination provides complete broad-spectrum antimicrobial protection equivalent to 1.5% Phenoxyethanol alone, with significantly reduced irritation potential.
Q2: Can Ethylhexylglycerin be used as a standalone preservative?
A: Ethylhexylglycerin has mild inherent antimicrobial activity but is not effective as a sole preservative for most formulations. It is designed as a booster to enhance other preservatives. For complete preservation, always combine with Phenoxyethanol, benzyl alcohol, sodium benzoate, or other primary preservatives.
Q3: What is the maximum safe usage level in cosmetics?
A: There is no regulatory maximum limit for Ethylhexylglycerin in most regions. However, typical usage ranges from 0.1-0.5% for preservative boosting and up to 2.0% for moisturizing/conditioning benefits. Levels above 2% may cause temporary skin warming or tingling sensations in sensitive individuals.
Q4: Is Ethylhexylglycerin suitable for natural and organic cosmetics?
A: Yes, Ethylhexylglycerin is widely accepted in natural and organic cosmetics. It is approved for use in Ecocert, COSMOS, and NATRUE certified formulations, making it the preservative booster of choice for clean beauty brands.
Q5: Does Ethylhexylglycerin cause skin irritation or sensitization?
A: When used at recommended levels (0.1-1.0%), Ethylhexylglycerin has an excellent safety profile with extremely low irritation potential. Some individuals may experience mild, transient warming or tingling, but this is not true sensitization. Our high-purity grade minimizes this effect.
Q6: Can Ethylhexylglycerin be used in baby products and wet wipes?
A: Absolutely, Ethylhexylglycerin is one of the most recommended ingredients for baby wipes and infant care due to its exceptional mildness. It is widely used in premium baby wipe formulations at 0.1-0.3% to boost preservation while maintaining skin gentleness.
Q7: How does Ethylhexylglycerin work as a deodorant?
A: Unlike aluminum-based antiperspirants that block sweat glands, Ethylhexylglycerin works by selectively inhibiting the growth of Corynebacterium and other odor-causing bacteria on the skin surface, without disrupting the natural skin microbiome or affecting normal sweating.
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