Pyrrolidinyl Diaminopyrimidine Oxide-CAS 115970-15-1
Product Name: Pyrrolidinyl Diaminopyrimidine Oxide
Abbreviation: PDO
INCI Name: Pyrrolidinyl Diaminopyrimidine Oxide
CAS No.: 115970-15-1
Grade: Cosmetic Premium Grade (High-Purity Professional Anti-hair Loss)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Uniform Fineness, No Caking, Odorless, Pure Texture
Molecular Formula: C₈H₁₄N₆O
Molecular Weight: 214.24
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent water solubility, completely soluble in room-temperature pure water, clear and transparent solution; stable compatibility with surfactants, moisturizers and various water-based hair care formula systems, no precipitation or stratification
Core Efficacy: Activate dormant hair follicles, prolong hair growth cycle, strengthen hair root fixation, reduce pathological hair loss, relieve scalp inflammation and itching, improve scalp microcirculation, promote healthy hair regeneration
Key Characteristics: Upgraded high-efficiency pyrimidine anti-hair loss active, dual mechanism of follicle activation and scalp anti-inflammation, non-hormonal, zero dependence, mild and non-irritating, low dosage and high efficiency, stable formula performance, suitable for long-term scalp maintenance
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and activity attenuation
Shelf Life: 24 Months
Application: Widely used in anti-hair loss shampoo, scalp care essence, hair growth serum, anti-hair loss conditioner, scalp soothing and anti-inflammatory hair care functional formulas
Pyrrolidinyl Diaminopyrimidine Oxide, PDO, Cosmetic Grade PDO, Anti-hair Loss Ingredient, Follicle Activator, Scalp Anti-inflammatory, Hair Root Strengthening, Hair Growth Active Raw Material
Pyrrolidinyl Diaminopyrimidine Oxide-CAS 115970-15-1
Cosmetic Grade Pyrrolidinyl Diaminopyrimidine Oxide (PDO) is a new upgraded high-efficiency non-hormonal anti-hair loss and hair growth active ingredient, optimized and upgraded on the basis of traditional diaminopyrimidine oxide (DPO).
It innovatively introduces pyrrolidinyl functional groups to achieve dual core effects of follicle activation and scalp inflammation repair, solving the single efficacy defect of traditional anti-hair loss ingredients.
PDO can efficiently penetrate the scalp epidermal tissue, target dormant and atrophic hair follicle cells, significantly prolong the hair growth anagen cycle, inhibit premature follicle apoptosis, and fundamentally improve diffuse hair loss, sparse hair and hair follicle atrophy problems caused by fatigue, stress and scalp inflammation.
Meanwhile, it can effectively relieve scalp inflammatory reactions, improve scalp itching, redness and oily swelling caused by bacterial proliferation and external stimulation, balance scalp oil-water microecology, and create a clean and healthy growth environment for hair roots.
Different from hormone anti-hair loss ingredients, PDO has mild properties, no scalp dependence, no irritation and no side effects after long-term use. It has ultra-high water solubility and excellent formula compatibility, does not affect the viscosity, transparency and fragrance of finished hair care products, and is a high-end core active raw material for professional medical-grade anti-hair loss and scalp healthy maintenance hair care products.



Key Benefits
• Upgraded Dual-efficiency Mechanism, More Comprehensive Anti-hair Loss: Compared with ordinary DPO single hair fixation effect, PDO adds powerful scalp anti-inflammatory function, solves inflammatory hair loss and scalp itching problems, realizes integration of hair fixation, anti-loss and scalp maintenance.
• Root Follicle Activation, Reverse Follicle Atrophy: Target dormant hair follicles, wake up inactive follicle vitality, prolong hair growth cycle, fundamentally improve sparse hair and fine and soft hair, and promote new hair germination.
• Strengthen Hair Root Adhesion, Reduce Shedding Greatly: Enhance the binding force between hair root and scalp dermis, firm loose hair roots, significantly reduce washing and combing hair loss, and improve frequent hair shedding.
• Relieve Scalp Inflammation, Stabilize Scalp Health: Inhibit scalp harmful bacteria reproduction, relieve oily inflammation, redness and itching, balance scalp oil secretion, and improve sub-health scalp state.
• Non-hormonal & Zero Dependence, Safe for Long-term Use: Pure cosmetic synthetic active, hormone-free, non-irritating, non-sensitizing, no follicle inertia after long-term use, safe for oily scalp, sensitive scalp and fragile scalp.
Excellent Water Solubility & High Formula Stability: Fully soluble in room temperature water, stable in full pH range, compatible with all shampoo and essence systems, convenient for industrial mass pro
Applications
• High-efficiency Anti-hair Loss Shampoo Series: Core functional active for professional anti-hair loss shampoo and oil-control anti-shedding cleansing products, stabilize hair roots while cleaning, improve inflammatory hair loss and oily scalp hair loss.
• Scalp Repair & Hair Growth Essence: Widely used in scalp care essence, hair growth stock solution and dense hair serum, activate atrophic follicles, repair inflamed scalp, and promote healthy hair regrowth.
• Anti-hair Loss Conditioner & Hair Mask: Added in nourishing conditioner and scalp care hair mask, strengthen hair shaft toughness, fix loose hair roots, and realize dual care of scalp and hair.
• Inflamed & Sensitive Scalp Care Products: Specially suitable for scalp itching, redness and oily inflammation care formulas, soothe scalp sensitivity, improve scalp microecology, and solve recurrent hair loss caused by inflammation.
• Post-stress & Postpartum Hair Loss Products: Effectively improve stress alopecia, postpartum diffuse hair loss and seasonal hair loss, activate follicle vitality, and restore healthy hair growth rhythm.
• Medical-grade Scalp Healthy Maintenance Formula: As high-end dual-effect anti-hair loss active, build professional medical-grade scalp anti-inflammation and hair fixing system, improve product core competitiveness.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Pyrrolidinyl Diaminopyrimidine Oxide | Compliant |
CAS No. | 115970-15-1 | Compliant |
Appearance | White Fine Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.63% |
Melting Point | 208℃~218℃ | 213.5℃ |
Loss on Drying | ≤0.5% | 0.12% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of PDO?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and anti-hair loss efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.1%-0.3% for anti-hair loss shampoo and conditioner; 0.2%-0.6% for scalp essence and hair growth serum, adjustable according to anti-inflammation and hair thickening efficacy requirements.
• Q4: What is the difference between PDO and DPO?
A4: PDO is an upgraded version of DPO. On the basis of DPO's hair root strengthening and anti-hair loss effect, it adds powerful scalp anti-inflammatory and soothing effects, specifically improves inflammatory scalp hair loss, with more comprehensive efficacy and wider applicability.
• Q5: Is PDO hormonal and dependent?
A5: No, PDO is a high-purity non-hormonal cosmetic active ingredient, mild in nature, no addiction and no scalp dependence after long-term use, safe for daily scalp maintenance.
• Q6: Is it suitable for oily and itchy scalp?
A6: Absolutely yes. PDO can effectively inhibit scalp inflammation, relieve oil itching and redness, balance scalp oil secretion, and is especially suitable for oily inflamed scalp and sensitive scalp anti-hair loss formulas.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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