Glycyrrhetinic Acid-CAS 471-53-4
Glycyrrhetinic Acid
CAS No. 471-53-4
molecular formula C₃₀H₄₆O₄
molecular weight 470.68
purity ≥98.0%
white crystalline powder, odorless and tasteless, insoluble in water, soluble in ethanol, chloroform and pyridine, with stable physical and chemical properties
Glycyrrhetinic Acid-CAS 471-53-4
Glycyrrhetinic Acid-CAS 471-53-4
Glycyrrhetinic Acid is a core functional active substance derived from natural licorice, known as a classic plant soothing and anti-inflammatory ingredient in the global cosmetic and pharmaceutical industries. Different from ordinary plant extracts, high-purity Glycyrrhetinic Acid has stable efficacy, strong skin affinity and significant transdermal absorption. It can alleviate various skin discomforts caused by external stimulation, inhibit melanin precipitation, and achieve the dual effects of soothing repair and brightening skin tone. It is an indispensable raw material for high-end soothing, repair and brightening skincare formulas.
Key Benefits
• Excellent Skin Repair Capacity: Repairs damaged skin barrier, reduces external stimulus damage, improves fragile skin and enhances skin tolerance.
• Antioxidant & Brightening Efficacy: Scavenges skin free radicals, inhibits melanin aggregation and precipitation, fades dullness and evens skin tone.
• Ultra-Low Irritation & High Safety: Natural plant-derived ingredient, mild and non-irritating, compliant with global safety standards, suitable for sensitive skin formula development.
• Stable Formula Compatibility: Good compatibility with most cosmetic and pharmaceutical raw materials, stable efficacy in oil-phase formulas, no adverse reactions after compounding.
• High Purity & Stable Batch Quality: Industrial high-purity purification process, low impurity content, consistent active content in each batch, ensuring stable finished product efficacy.
Applications
• Soothing & Repairing Skincare Products: Core ingredient for soothing essence, barrier repair cream, after-sun repair lotion and sensitive skin care products to relieve skin sensitivity and redness.
• Brightening & Whitening Cosmetics: Applied in brightening lotion, whitening cream and spot-fading formulas to assist in diluting pigmentation and brightening complexion.
• Anti-Aging Functional Products: Added in anti-aging and antioxidant skincare formulas to resist free radical damage and delay skin photoaging.
• High-End Daily Chemical Products: Suitable for high-end facial care, body care and mild skincare products to upgrade product soothing and repair efficacy.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result | Test Method |
Product Name | Glycyrrhetinic Acid (18β-Type) | Compliant | Visual Verification |
CAS No. | 471-53-4 | Compliant | Document Verification |
Appearance | White Crystalline Powder, Odorless | Compliant | Visual Inspection |
Purity (HPLC) | ≥98.0% | 98.72% | High Performance Liquid Chromatography |
Loss on Drying | ≤1.0% | 0.31% | Drying Weight Loss Method |
Residue on Ignition | ≤0.5% | 0.12% | High Temperature Ignition Method |
Heavy Metal (Pb) | ≤10ppm | <5ppm | Atomic Absorption Spectrometry |
Arsenic (As) | ≤2ppm | <1ppm | Atomic Absorption Spectrometry |
Total Microbial Count | ≤100CFU/g | Compliant | Microbial Culture Method |
Conclusion | Conforms to Global Cosmetic & Pharmaceutical Grade Standards | Qualified | Comprehensive Detection |
Frequently Asked Questions (FAQ)
• Q1: What grade standards does your Glycyrrhetinic Acid comply with? A1: It meets cosmetic and pharmaceutical grade standards, compliant with FDA, EU SCCS and NMPA regulations.
• Q2: What is the MOQ and delivery time? A2: MOQ is 1KG, sufficient spot stock supports bulk orders and fast global delivery.
• Q3: What formula systems is this ingredient suitable for? A3: Mainly applicable to oil-phase formulas, compatible with various skincare and pharmaceutical compound formulas.
• Q4: What are the standard storage conditions and shelf life? A4: Sealed and stored in cool dry dark place, with a shelf life of 24 months.
• Q5: Can you provide complete export certification documents? A5: Full set of COA, MSDS, test reports and customs clearance documents are available.
• Q6: What is the recommended addition ratio in formulas? A6: Conventional addition ratio is 0.05%-0.5%, adjustable according to product efficacy requirements.
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