Hydroxypropyl Chitosan-CAS 9012-76-4
Product Name: Hydroxypropyl Chitosan
Abbreviation: HP Chitosan
INCI Name: Hydroxypropyl Chitosan
CAS No.: 9012-76-4
Grade: Cosmetic Premium Grade (High Purity Water-soluble Type)
Purity: ≥98.0%
Appearance: White to Off-White Loose Powder, Uniform Fineness, No Caking, Slight Characteristic Odor
Molecular Formula: Variable (Modified Chitosan Polymer)
MOQ (Minimum Order Quantity): 25KG
Solubility: Completely water-soluble, no heating required, fast dissolution, clear and transparent aqueous solution; excellent compatibility with most water-soluble cosmetic active ingredients and surfactants
Core Efficacy: Long-lasting moisturizing and water locking, rapid skin barrier repair, anti-inflammatory and soothing redness, uniform film-forming protection, anti-oxidation anti-aging, inhibit bacterial growth
Key Characteristics: Propyl-modified chitosan structure, perfectly solve the defect of insoluble traditional chitosan; high skin affinity, breathable invisible film, non-sticky, anti-allergy and soothing, promote keratin repair, excellent formula stability
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and agglomeration
Shelf Life: 24 Months
Application: Widely used in barrier repair lotion, soothing cream, medical beauty post-repair products, facial mask essence, anti-sensitive skincare, anti-aging functional formulas and daily moisturizing cosmetics
Hydroxypropyl Chitosan, Water-soluble Chitosan, Cosmetic Grade Hydroxypropyl Chitosan, Skin Barrier Repair Agent, Moisturizing Film-forming Agent, Anti-inflammatory Soothing Raw Material, Anti-aging Skincare Ingredient
Hydroxypropyl Chitosan-CAS 9012-76-4
Cosmetic Grade Hydroxypropyl Chitosan is a high-performance water-soluble modified natural polysaccharide polymer, upgraded and optimized based on traditional chitosan.
Traditional chitosan is only soluble in acidic solutions and difficult to apply in neutral and mild cosmetic formulas, while hydroxypropyl chitosan introduces hydrophilic hydroxypropyl groups through molecular modification, realizing full water solubility at room temperature without acid dissolution, which greatly expands cosmetic application scenarios.
It has excellent skin-fitting and film-forming properties, can form a breathable, invisible and flexible protective film on the skin surface, effectively lock skin moisture, reduce transdermal water loss, and achieve long-lasting moisturizing effect.
With natural biological activity, it can penetrate the superficial skin layer to repair damaged keratin gaps, soothe skin redness, swelling and sensitivity caused by external stimulation, and accelerate skin barrier recovery.
In addition, it has mild antibacterial, anti-inflammatory and antioxidant effects, which can inhibit the growth of harmful bacteria on the skin surface, reduce inflammatory reactions, scavenge free radicals, delay skin aging, and improve dull and loose skin texture.
The product has mild properties, no irritation, no stickiness after application, stable formula performance, and will not affect the transparency and texture of finished products. It is an indispensable core raw material for sensitive skin soothing repair, medical beauty postoperative maintenance and high-efficiency moisturizing anti-aging skincare formulas.



Key Benefits
• Full Water Solubility, Easy Formula Processing: Break through the limitation of traditional chitosan, soluble in pure water at room temperature without acid adjustment, simple operation, no precipitation and stratification, suitable for all kinds of neutral and mild cosmetic systems.
• Breathable Film-forming & Long-lasting Moisturizing: Form invisible flexible protective film on skin surface, lock moisture efficiently, reduce dryness and tightness, moisturize for a long time without greasy and sticky residue, optimize skin touch.
• Rapid Barrier Repair & Soothing Anti-sensitivity: Targetedly repair damaged keratin barrier, relieve redness, dry itch and sensitive discomfort caused by external stimulation and medical beauty irritation, accelerate skin recovery.
• Mild Antibacterial & Anti-inflammatory: Natural biological antibacterial activity, inhibit the reproduction of skin harmful bacteria, reduce skin inflammatory problems, improve acne and sensitive skin microenvironment safely and mildly.
• Anti-oxidation & Anti-aging: Effectively scavenge skin free radicals, delay collagen loss, improve skin dullness and looseness, firm skin texture, and present delicate and young skin state.
• High Compatibility & Stable Formula: Excellent compatibility with water-soluble actives, moisturizers and surfactants, stable performance in wide pH range, no discoloration and deterioration during long-term storage.
Applications
• Sensitive Skin Repair Skincare Series: Core repairing raw material for barrier repair lotion, soothing toner, anti-sensitive cream and redness-relieving products, stabilize fragile skin and improve skin tolerance.
• Medical Beauty Post-operation Repair Products: Widely used in medical repair essence, repair mask and postoperative soothing lotion, relieve redness and swelling, accelerate skin wound healing and barrier reconstruction.
• Daily Moisturizing & Hydrating Products: Added in moisturizing lotion, nourishing cream, hydrating essence and facial mask, long-term lock water, improve dry and rough skin, keep skin moist and tender.
• Anti-aging & Brightening Functional Formulas: Applied in anti-aging essence and firming skincare products, scavenge free radicals, delay aging, improve dull and loose skin, and brighten skin tone.
• Mild Antibacterial & Acne-soothing Products: Suitable for mild acne-soothing lotion and oily skin care products, inhibit harmful bacteria growth, relieve mild inflammation, balance skin microecology.
• High-end Clean Beauty Skincare: As natural green functional raw material, replace synthetic soothing and moisturizing ingredients, build mild, safe and efficient clean beauty skincare system.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Hydroxypropyl Chitosan | Compliant |
CAS No. | 9012-76-4 | Compliant |
Appearance | White to Off-White Uniform Powder | Compliant |
Purity | ≥98.0% | 98.75% |
Moisture Content | ≤5.0% | 2.16% |
Ash Content | ≤1.0% | 0.32% |
Water Solubility | Fully Soluble, Clear Solution | Qualified |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Microorganism | ≤100CFU/g, No Pathogenic Bacteria | Qualified |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Hydroxypropyl Chitosan?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and skincare efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.1%-0.5% for toner, essence and mask; 0.2%-0.8% for repair cream and lotion, adjustable according to moisturizing and repairing efficacy requirements.
• Q4: What is the difference from ordinary chitosan?
A4: Ordinary chitosan is only soluble in acid water with poor applicability; hydroxypropyl chitosan realizes room-temperature water solubility, milder properties, no irritation, better film-forming and repairing effect, suitable for all mild cosmetic formulas.
• Q5: Will it cause sticky skin feeling after use?
A5: No, the product has moderate film-forming flexibility, fresh and non-sticky skin feeling, will not cause heavy or sticky residue, and can optimize the slippery texture of finished products.
• Q6: Is it suitable for medical beauty repair sensitive skin products?
A6: Yes, high-purity modified natural raw material, non-irritating and non-sensitizing, excellent barrier repair and soothing effect, specially suitable for postoperative fragile skin and sensitive skin maintenance.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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