Palmitoyl Tripeptide-5 Anti-Aging Firming Collagen Boosting Wrinkle Repair Cosmetic Raw Material(CAS 221227-05-0)
Product Name: Palmitoyl Tripeptide-5 High-Purity Collagen Activating Anti-Wrinkle Firming Active Raw Material
INCI Name: Palmitoyl Tripeptide-5
Alias: Palmitoyl Tripeptide 5, Collagen Boosting Peptide, Anti-Wrinkle Polypeptide, Skin Lifting Firming Factor, Dermis Repair Peptide, Anti-Aging Anti-Laxity Raw Material
CAS No.: 221227-05-0 (Palmitoyl Tripeptide-5)
Appearance: Colorless and transparent aqueous solution, clean and free of impurities, odorless and pure texture, uniform and stable liquid state.
Grade: Cosmetic Premium Grade
MOQ (Minimum Order Quantity): 25KG
Solubility: Fully soluble in water and conventional polar cosmetic solvents, completely compatible with all water-phase skincare systems and partial mild oil-phase formulas.
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, storage temperature 5–25℃, avoid direct strong sunlight irradiation, high temperature heating and damp environment. Keep tightly sealed after opening to prevent microbial contamination and active peptide attenuation, avoid long-term air exposure and oxidative inactivation, and ensure long-term stable anti-wrinkle and firming efficacy of the product.
Shelf Life: 24 Months
Palmitoyl Tripeptide-5, Collagen Peptide, Anti-Wrinkle, Firming Lifting, Anti-Aging, Skin Elasticity Improvement, Wrinkle Repair, Cosmetic Peptide Raw Material
Palmitoyl Tripeptide-5 Anti-Aging Firming Collagen Boosting Wrinkle Repair Cosmetic Raw Material(CAS 221227-05-0)
Palmitoyl Tripeptide-5 is a classic high-efficiency collagen regenerating anti-aging polypeptide in the skincare industry, belonging to lipophilic modified small-molecule active peptide.
Different from common moisturizing anti-aging ingredients and surface wrinkle-fading components, it focuses on solving dermal aging problems.
It realizes the three major core advantages of activating fibroblast proliferation, promoting endogenous collagen synthesis, repairing dermal fiber structure and tightening skin contour.
It efficiently solves the pain points of ineffective improvement of static wrinkles, persistent skin laxity, insufficient skin elasticity and slow dermal repair of ordinary anti-aging raw materials.
With excellent transdermal penetration, it can directly act on the dermal layer, awaken skin cell vitality, continuously replenish skin collagen, reverse aging sagging texture, and make the skin tight, smooth and elastic.
With ultra-high safety, mild efficacy and excellent formula synergy, it is the mainstream core peptide raw material for upgrading high-end firming and anti-wrinkle anti-aging skincare products.



Key Benefits
• Activate Fibroblasts, Boost Collagen Regeneration: Precisely act on skin dermal fibroblasts, effectively activate cell proliferation and metabolic vitality, significantly promote the synthesis and regeneration of endogenous collagen and elastin, replenish skin collagen loss from the source, and build a solid dermal fiber support network.
• Fade Static Wrinkles, Refine Aging Texture: Targetedly improve static fine lines, dry lines and shallow nasolabial folds formed by long-term collagen loss, fill skin microscopic gaps from the dermis, smooth rough aging texture, and restore skin delicate and smooth touch.
• Lift and Firm, Improve Sagging Contour: Repair fractured and loose dermal elastic fiber network, enhance skin tissue tension and supporting force, effectively improve facial sagging, jowl looseness and contour collapse problems, tighten facial lines, and create a compact three-dimensional facial contour.
• Deep Dermal Repair, Delay Skin Aging: Act on the root of dermal aging, continuously repair aging and damaged skin tissues, block the continuous deterioration of skin aging, effectively delay the formation of new wrinkles and sagging problems, and realize long-term anti-aging maintenance.
• Small Molecule High Absorption, Efficient Anti-Aging: Modified lipophilic small-molecule peptide structure, with strong transdermal penetration and high skin affinity, can quickly reach the dermal layer to exert efficacy, no surface accumulation, high utilization rate, and more significant anti-wrinkle and firming effect than ordinary macromolecule peptides.
Mild Safe & Strong Compatibility, Upgrade Product Value: Artificial high-purity synthetic peptide, zero irritation, zero sensitization, safe for long-term use. It can be compounded with various anti-aging, antioxidant and repair ingredients to build a full-dimensional anti-wrinkle, firming and anti-aging system, comprehensively improving product efficacy and high-end market competitiveness.
Applications
• Anti-Wrinkle & Fine Line Repair Series: Core functional peptide raw material for anti-static wrinkle and fine line fading essence and cream. It targets dermal aging and fundamentally improves various aging lines.
• Firming Lifting & Anti-Laxity Products: Key active ingredient for facial contour tightening, sagging improvement and skin elasticity restoration formulas, dedicated to solving skin sagging and contour collapse problems.
• High-Efficiency Dermal Anti-Aging System: Exclusive dermal repair and collagen boosting active for deep anti-aging skincare products, realizing inner repair and outer firming anti-aging effect.
• Elasticity Restoration & Anti-Aging Maintenance Series: Preferred raw material for improving skin dullness, rigidity and insufficient elasticity, activating skin vitality and restoring skin bouncy and tender state.
• Mature Skin Anti-Aging Products: Special anti-aging active for mature aging skin, effectively improving aging problems such as relaxation, wrinkles and loss of elasticity in mature skin.
• Compound Polypeptide Anti-Aging Synergistic System: Professional synergist for multi-peptide compound anti-aging formulas, cooperating with firming and anti-oxidation ingredients to amplify comprehensive anti-aging efficacy in an all-round way.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Palmitoyl Tripeptide-5 | Compliant |
Appearance | Colorless Transparent Liquid, Odorless | Compliant |
Peptide Content (%) | ≥99.0 (Customizable) | 99.3 |
Loss on Drying (%) | ≤0.5 | 0.18 |
pH Value (1% Aqueous Solution) | 5.0–7.0 | 5.9 |
Heavy Metal (Pb) | ≤1ppm | 0.1ppm |
Arsenic (As) | ≤0.5ppm | Not Detected |
Mercury (Hg) | ≤0.1ppm | Not Detected |
Cadmium (Cd) | ≤0.1ppm | Not Detected |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Palmitoyl Tripeptide-5?
A1: The standard MOQ is 25KG, support sample orders for formula testing, anti-wrinkle firming efficacy debugging and finished product trial production, and support customized concentration specifications for mass production.
• Q2: What is the core formula positioning of Palmitoyl Tripeptide-5?
A2: It is a high-efficiency dermal anti-aging polypeptide raw material integrating collagen regeneration, static wrinkle fading, facial lifting and firming, elasticity restoration. It focuses on solving dermal aging problems such as collagen loss, static wrinkle growth, facial sagging and insufficient skin elasticity, and is used for high-end firming anti-wrinkle and mature skin anti-aging formula upgrading.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional anti-aging maintenance: 0.05%–0.2%; High-efficiency anti-wrinkle firming essence: 0.2%–0.5%; Lifting anti-laxity cream series: 0.3%–0.8%; Mature skin anti-aging products: 0.2%–0.6%, adjustable according to product efficacy positioning and formula system.
• Q4: What is the difference between Palmitoyl Tripeptide-5 and ordinary anti-aging ingredients?
A4: Ordinary anti-aging ingredients mostly act on the skin surface, only have moisturizing and temporary wrinkle smoothing effects, and cannot improve dermal collagen loss and static wrinkles. Palmitoyl Tripeptide-5 acts directly on the dermal layer, activates fibroblast collagen synthesis from the source, fundamentally solves static wrinkles and sagging aging, with more thorough and long-lasting anti-aging efficacy.
• Q5: What raw materials is it suitable for compounding?
A5: It is highly compatible with multi-peptide anti-aging combinations, hyaluronic acid, ergothioneine, bifida ferment lysate and antioxidant ingredients. The compound system can form a closed-loop anti-aging system of "collagen regeneration + wrinkle removal + firming lifting + barrier repair + anti-oxidation", significantly improving product anti-aging depth and comprehensive efficacy.
• Q6: What are the formula usage notes?
A6: Water-phase feeding at room temperature to 60℃ is recommended; avoid long-term high temperature above 80℃ to prevent peptide activity attenuation; suitable for weak acid and neutral formula systems to maximize collagen activating efficacy; compounded with moisturizing and firming ingredients for better superposition anti-aging effect.
• Q7: Can it provide stable supply and professional technical support?
A7: Strictly control core indicators such as peptide purity, pH value and heavy metals to ensure consistent batch stability. Support long-term bulk order supply, and provide one-stop professional services including anti-wrinkle firming formula optimization, anti-aging efficacy upgrading, formula debugging and after-sales technical guidance.
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