Isosorbitol Dimethyl Ether, DMI(CAS 5306-85-4)
Product Name: Isosorbitol Dimethyl Ether (DMI)
INCI Name: Dimethyl Isosorbide
CAS No.: 5306-85-4
Grade: Cosmetic Premium Grade (High-efficiency Penetration & Solubilization Special)
Purity: ≥99.5% High Purity
Appearance: Colorless Transparent Low-viscosity Liquid, Odorless, Pure and Clear Without Impurities, Excellent Fluidity
Molecular Formula: C₈H₁₄O₄
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent universal solubility, miscible with water, ethanol and most cosmetic oil-phase solvents in any proportion; strong solubilizing capacity for insoluble actives; stable in full pH range, no hydrolysis, stratification or precipitation; ultra-high compatibility with retinol, nicotinamide, whitening and antioxidant actives, easy formula deployment for industrial mass production
Core Efficacy: High-efficiency transdermal penetration boosting, significantly improve the skin absorption rate of functional active ingredients; powerful solubilization effect on insoluble cosmetic raw materials; optimize skin feel, reduce stickiness of high-efficiency formulas; stabilize active ingredients, avoid oxidation and inactivation; assist brightening and anti-oxidation, improve dull and sallow skin tone
Key Characteristics: Bio-based green solvent derived from sugarcane glucose fermentation; superior penetration enhancement effect compared with traditional ethanol and propylene glycol; non-volatile, non-irritating, non-degreasing; no dry and tight feeling after use; effectively solve the problems of poor solubility and low absorption of high-efficiency actives; stabilize photosensitive and heat-sensitive ingredients, greatly improve formula efficacy and product durability
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, freezing and long-term strong light exposure; keep tightly sealed after opening to prevent dust contamination and ensure liquid purity
Shelf Life: 24 Months
Application: Widely used in high-efficiency whitening essence, retinol anti-aging products, antioxidant formulas, sunscreen products, functional skincare with insoluble actives, high-permeability and low-irritation cosmetic systems
Isosorbitol Dimethyl Ether, Dimethyl Isosorbide, DMI, Penetration Enhancer, Cosmetic Solvent, Active Absorption Booster, Skin Brightening, Formula Stabilizer, Low Irritation Cosmetic Raw Material
Isosorbitol Dimethyl Ether, DMI(CAS 5306-85-4)
Cosmetic Grade Isosorbitol Dimethyl Ether (DMI) is a high-purity bio-based green functional solvent and penetration enhancer refined from natural sugarcane fermentation sources.
As a premium alternative to traditional volatile solvents such as ethanol and propylene glycol, DMI has unique bicyclic molecular structure, which endows it with powerful transdermal delivery and solubilization capabilities.
It can efficiently carry high-molecular and insoluble active ingredients such as retinol, vitamin derivatives and plant polyphenols to penetrate the stratum corneum, solve the problems of low skin absorption and poor efficacy exertion of traditional skincare actives.
Different from irritating volatile solvents, DMI is non-volatile and non-degreasing, with ultra-mild skin affinity, will not damage skin barrier or cause dryness and tightness.
Meanwhile, it can form a stable protective system for heat-sensitive and photosensitive ingredients, effectively prevent active oxidation and deactivation, improve formula uniformity and clarity, and optimize product refreshing skin feel. With high safety, wide compatibility and significant efficacy amplification advantages, DMI has become an indispensable core functional raw material for high-end high-efficiency skincare formulas.
Key Benefits
• Powerful Penetration Boosting, Amplify Efficacy: Unique bicyclic structure accelerates transdermal absorption of various actives, solves the problem of low utilization rate of skincare ingredients, and maximizes the efficacy of high-value formulas.
• Excellent Solubilization & Clarification: Efficiently dissolve insoluble plant extracts, retinol and functional actives, prevent formula turbidity and precipitation, keep finished products clear and stable for a long time.
• Mild & Non-irritating, Barrier-friendly: Bio-based green raw material, non-volatile and non-degreasing, no dry and tight feeling, no skin irritation or sensitization, suitable for sensitive skin formulas.
• Stabilize Sensitive Actives, Extend Shelf Life: Effectively protect photosensitive and heat-sensitive ingredients from oxidation and decomposition, stabilize formula activity, and improve product storage durability.
• Optimize Skin Feel, Refine Product Texture: Replace sticky traditional solvents, reduce greasiness of high-concentration active formulas, endow products with refreshing and non-sticky skin feel.
• Wide Compatibility & High Stability: Miscible with water and oil phases, stable in full pH range, compatible with all mainstream skincare actives, suitable for large-scale industrial formula production.
Applications
• High-efficiency Anti-aging Series: Core penetration enhancer for retinol, peptide and vitamin anti-aging essences, accelerate active absorption, maximize anti-wrinkle and firming efficacy, and stabilize retinol activity.
• Whitening & Brightening Functional Products: Applied in high-efficiency whitening formulas with plant extracts and brightening actives, promote transdermal delivery of whitening ingredients, improve dull and sallow skin, and uniform skin tone.
• Antioxidant Skincare Products: Used in polyphenol and antioxidant formulas, solve the solubility and stability problems of insoluble antioxidants, enhance free radical scavenging capacity, and delay skin aging.
• Sunscreen & Post-sun Repair Products: Assist in dissolving sunscreen agents, improve formula uniformity and coating feel, stabilize sunscreen active ingredients, and enhance sun protection durability.
• Mild Sensitive Skin Skincare: Replace irritating ethanol solvent, maintain formula mildness, ensure efficient absorption of actives without damaging the skin barrier, suitable for fragile skin care.
• Compound High-efficiency Formula System: Perfectly compounded with niacinamide, tranexamic acid, retinol, plant extracts and hyaluronic acid to build high-permeability, high-stability and high-efficiency skincare system.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Isosorbitol Dimethyl Ether (DMI) | Compliant |
CAS No. | 5306-85-4 | Compliant |
Appearance | Colorless Transparent Odorless Liquid | Compliant |
Purity | ≥99.5% | 99.82% |
Moisture Content | ≤0.1% | 0.06% |
Refractive Index | 1.458~1.462 | 1.460 |
pH Value | 6.0~7.5 | 6.8 |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Isosorbitol Dimethyl Ether?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 3%-8% for daily skincare formulas; 8%-15% for high-efficiency penetration-enhancing essences and insoluble active formulas, adjustable according to formula solubility and efficacy requirements.
• Q4: What is the difference between DMI and ethanol / propylene glycol?
A4: Traditional solvents are volatile and easy to cause skin dryness and irritation; DMI is non-volatile, non-degreasing and milder, with stronger penetration and solubilization capabilities, and can stabilize active ingredients, which is an upgraded green solvent for high-end formulas.
• Q5: Is DMI suitable for sensitive skin and facial resident formulas?
A5: Absolutely yes. It has passed strict cosmetic safety tests, ultra-mild and non-irritating, suitable for facial leave-on products and sensitive skin skincare formulas with high safety requirements.
• Q6: What ingredients is DMI suitable for compounding?
A6: It is especially suitable for compounding with retinol, plant polyphenols, whitening extracts and oil-soluble actives, which can significantly improve active solubility and transdermal absorption efficiency.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized bio-fermentation and purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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