Isosorbide Dimethyl Ether-CAS 5306-85-4
Common Name: Isosorbide Dimethyl Ether, DMI
Chemical Name: 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
CAS Number: 5306-85-4
Molecular Formula: C8H14O4
Molecular Weight: 174.19 g/mol
Purity: ≥99.0% Cosmetic & Industrial Grade
Appearance: Colorless transparent low-viscosity liquid, odorless
Boiling Point: 238–242℃
Solubility: Miscible with water, ethanol and most organic solvents
pH Value (1% Aqueous Solution): 6.0–7.5
MOQ: 1KG
Key Properties: Bio-based green solvent, excellent penetration, low volatility, high safety, good compatibility with various raw materials
Applications: Widely used in cosmetic penetration enhancers, daily chemical solvents, coating additives and green industrial solvent fields
Isosorbide Dimethyl Ether (DMI)
Isosorbide Dimethyl Ether-CAS 5306-85-4
Isosorbide Dimethyl Ether (DMI) is a high-performance bio-based green solvent derived from renewable plant sugar sources. As a low-toxic, low-volatility and high-penetration functional auxiliary, it features excellent solvent power and universal compatibility with aqueous and oil-phase systems. It can effectively enhance the penetration and absorption efficiency of functional ingredients in cosmetic formulas, while optimizing formula texture and stability. With mild properties and eco-friendly degradability, it is a core sustainable raw material for high-end green daily chemicals and fine industrial formulations worldwide.

Key Benefits
• Superior Penetration Enhancement: Effectively boosts the transdermal penetration and activity of functional ingredients, improving cosmetic product efficacy.
• Excellent Dual-Phase Solubility: Miscible with water and organic solvents, solving formula turbidity and layering problems efficiently.
• Low Volatility & High Stability: Low evaporation rate, stable formula performance during long-term storage, no ingredient loss.
• Ultra-Mild & Safe: Low-toxic and non-irritating, suitable for sensitive skin formulas and high-standard daily chemical products.
• Good Formula Compatibility: Compatible with surfactants, emulsifiers and various functional additives, easy for formula debugging and mass production.
• Bio-Based & Eco-Friendly: Renewable raw material source, fully biodegradable, compliant with global green environmental protection standards.
Applications
• High-End Skincare Products: Used in essence, serum, moisturizing lotion and repair cream as penetration enhancer and solvent to improve ingredient utilization.
• Mild Cosmetic Formulas: Applied in sensitive skin care products and low-irritation daily cosmetics to optimize mildness and texture.
• Color Cosmetics: Serves as high-efficiency solvent and dispersant for foundation, lipstick and eye makeup to improve color uniformity.
• Daily Chemical Products: Added in hair care and body care products to enhance ingredient penetration and product comprehensive performance.
• Green Industrial Formulation: Used as eco-friendly solvent and additive for environmental coatings, fine chemical synthesis and polymer processing.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result | Test Method |
Product Name | Isosorbide Dimethyl Ether (DMI) | Compliant | Visual Verification |
CAS No. | 5306-85-4 | Compliant | Document Verification |
Appearance | Colorless Transparent Liquid, Odorless | Compliant | Visual & Olfactory Inspection |
Purity | ≥99.0% | 99.68% | HPLC Method |
pH Value (1% Aqueous Solution) | 6.0–7.5 | 6.72 | pH Meter Test |
Moisture Content | ≤0.1% | 0.02% | Karl Fischer Method |
Heavy Metal (Pb) | ≤10ppm | <5ppm | Atomic Absorption Spectrometry |
Residue on Ignition | ≤0.05% | 0.03% | High Temperature Calcination Method |
Inspection Conclusion | Conforms to Global Cosmetic & Industrial Grade Standards | Qualified | Comprehensive Detection |
Frequently Asked Questions (FAQ)
• Q1: Can you customize DMI purity and packaging specifications? A1: Custom purity grades and packaging options are available for diverse industrial and cosmetic formulas.
• Q2: What is your bulk order delivery capacity? A2: 1KG MOQ, sufficient spot stock supports large-batch orders and global fast shipping.
• Q3: What full-set export documents can you provide? A3: Complete COA, MSDS and customs clearance documents are provided for global trade.
• Q4: What are the standard storage conditions and shelf life? A4: 24-month shelf life, store sealed in cool, dry and shaded environment.
• Q5: Is DMI compliant for global cosmetic export? A5: It meets international daily chemical safety standards for worldwide compliant sales.
• Q6: What is the conventional addition dosage in formulas? A6: Standard dosage ranges from 1.0%-8.0%, adjustable for different application scenarios.
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