Polydatin, Polygonum Cuspidatum Extract(CAS 27208-80-4)
Product Name: High-Purity Polydatin Natural Polygonum Cuspidatum Root Extract Multi-Effect Anti-Glycation Anti-Oxidation Brightening Anti-Aging Soothing Barrier Repair Cosmetic Raw Material
INCI Name: Polygonum Cuspidatum Root Extract
Alias: Polydatin Glycoside, Resveratrol Glycoside, Giant Knotweed Extract, High-Stability Antioxidant Factor, Anti-Glycation Brightening Active, Dullness Repair Ingredient, Mild Anti-Aging Raw Material
CAS No.: 27208-80-4
Appearance: Off-white to slight yellow fine uniform powder, pure texture, odorless or slight natural plant fragrance, excellent water solubility and superior transdermal permeability.
Grade: Cosmetic High-Purity Plant-Derived Grade
Source: This product is extracted and purified from the root of wild Polygonum Cuspidatum, a traditional high-value medicinal and homologous plant rich in natural polyphenol active substances.
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent water solubility, rapidly and uniformly dissolved in purified water and all water-phase cosmetic systems, clear and transparent colorless to slight yellow solution after dissolution without precipitation, turbidity and flocculation; perfectly compatible with oil-phase and emulsified formula systems, suitable for full-formula system application.
Storage Condition: Sealed storage in dry, cool and ventilated warehouse at 5–25℃, strictly avoid strong light direct irradiation, high temperature and high humidity damp environment to prevent powder moisture agglomeration and active polydatin attenuation. Keep tightly sealed after opening, isolate air and moisture, avoid long-term contact with oxygen leading to molecular oxidation and deactivation, and permanently stabilize anti-glycation yellowing removal, anti-oxidation brightening, barrier repair and anti-aging core efficacy.
Shelf Life: 24 Months
Polydatin, Polygonum Cuspidatum Extract, Anti-Glycation, High-Efficiency Anti-Oxidation, Brightening Whitening, Anti-Aging, Anti-Inflammatory Soothing, Skin Barrier Repair, Cosmetic Raw Material
Polydatin, Polygonum Cuspidatum Extract(CAS 27208-80-4)
Polydatin is a high-purity high-stability natural plant-derived multi-functional anti-glycation anti-yellowing, high-efficiency anti-oxidation, brightening uniform skin tone, soothing barrier repair and gentle anti-aging cosmetic active raw material.
Adopting low-temperature bionic wall-breaking extraction and high-precision molecular purification technology, it retains ultra-high biological activity and stable molecular structure of natural polydatin.
Breaking through the limitations of ordinary resveratrol with poor water solubility, unstable activity and single antioxidant efficacy, it innovatively builds a surface soothing and stabilizing + epidermal barrier repair + deep anti-glycation brightening + basal anti-oxidation anti-aging four-dimensional skin care system.
It can efficiently block skin glycation aging pathway, scavenge multi-layer oxidative free radicals, inhibit melanin uneven precipitation, repair damaged skin barrier, relieve inflammatory sensitivity, comprehensively improve glycation sallowness, oxidative dullness, fragile sensitivity and light aging problems.
With pure natural plant ultra-mild safety, exclusive high-stability anti-glycation & anti-oxidation advantages and excellent formula compounding stability, it is an irreplaceable core upgraded raw material for high-end anti-yellowing brightening, antioxidant anti-aging and sensitive skin repair functional skin care formulas.



Key Benefits
• High-Stability Anti-Oxidation, Eliminate Oxidative Dullness: Relying on unique stable glycoside molecular structure, it efficiently scavenges superficial and deep oxidative free radicals in the skin, inhibits lipid peroxidation and oxidative aging reaction, reduces gray dullness and dark complexion caused by environmental stress and aging accumulation, significantly improves skin clarity and restores translucent bright texture.
• Efficient Anti-Glycation & Anti-Yellowing, Purify Turbid Complexion: Precisely target skin glycation reaction, effectively inhibit the generation and accumulation of glycation end products (AGEs), block collagen glycosylation yellowing and cross-linking aging, improve long-term accumulated glycation sallowness and turbid skin tone, and solve the stubborn yellow dullness pain points that ordinary antioxidants cannot improve.
• Inhibit Melanin Precipitation, Brighten & Uniform Skin Tone: Regulate melanin cell activity, block the transfer and precipitation of superficial melanin, improve uneven skin tone, pigmentation and post-inflammatory dullness, naturally brighten skin tone, and make skin tone clean and uniform.
• Mild Anti-Inflammatory Soothing, Stabilize Sensitive Skin: Inhibit the release of superficial inflammatory factors, relieve acute redness, dry itching and stinging discomfort caused by external stimulation, seasonal changes and barrier damage, calm skin irritation, and enhance skin tolerance and stability.
• Barrier Damage Repair, Improve Fragile Skin: Promote the repair of damaged epidermal barrier gaps, accelerate the proliferation of skin keratinocytes, lock skin moisture, improve dry, tight and fragile skin caused by barrier loss, and rebuild skin healthy defense system.
• Gentle Anti-Aging Firming, Delay Light Aging: Dual anti-oxidation and anti-glycation anti-aging mechanism, resist dual aging of oxidation and glycation, improve loose skin and dry fine lines caused by light aging, lift skin contour, and maintain delicate and firm youthful skin state.
• Superior Formula Stability & Strong Compatibility: Compared with ordinary resveratrol, polydatin has ultra-high water solubility and light and thermal stability, stable activity in full pH range, no discoloration, precipitation or activity attenuation during high-temperature batching and long-term storage. The dissolved solution is clear and transparent, does not affect finished product appearance and high-grade texture, and can be perfectly compounded with multiple functional actives for synergistic efficacy upgrading.
Applications
• Anti-Glycation Anti-Yellowing Brightening Series: Core anti-glycation active for yellow and turbid skin, block collagen glycation aging, eliminate accumulated sallowness, purify turbid complexion, and restore skin translucent bright texture.
• Oxidative Dull & Uneven Tone Products: Applied in environmental stress dull skin formulas, scavenge multi-layer oxidative free radicals, fade gray dark dullness and pigmentation, uniform skin tone, and improve overall skin clarity.
• Sensitive Skin Barrier Repair Formulas: Professional barrier repair and soothing active for fragile sensitive skin, repair damaged epidermal barrier, relieve inflammatory redness and dry itching, and stabilize skin microecological balance.
• Light Anti-Aging Firming & Fine Line Refining Series: Used in early anti-aging skin care products, resist dual aging of glycation and oxidation, tighten loose skin, fade dry fine lines, and delay skin light aging process.
• Post-Inflammatory Repair & Brightening Products: Suitable for sensitive post-repair and dull brightening formulas, improve post-inflammatory pigmentation, soothe skin discomfort, and prevent dullness and darkening.
• High-End Multi-Active Compound Functional System: Synergistically compounded with centella hydroxycinnamic acid, morin, dandelion flavonoid, ginkgolide, bamboo leaf flavonoids and trametes versicolor polysaccharide to build a full-effect closed-loop system of anti-glycation brightening, anti-oxidation anti-aging, barrier repair, inflammatory soothing and delicate skin refining.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Polydatin (Polygonum Cuspidatum Root Extract) | Compliant |
Appearance | Off-White to Slight Yellow Fine Uniform Powder | Compliant |
Polydatin Content (%) | ≥98.0% (Customizable) | 98.62% |
Loss on Drying (%) | ≤0.5 | 0.15 |
Residue on Ignition (%) | ≤0.3 | 0.06 |
Heavy Metal (Pb) | ≤1ppm | 0.1ppm |
Arsenic (As) | ≤0.5ppm | Not Detected |
Mercury (Hg) | ≤0.1ppm | Not Detected |
Cadmium (Cd) | ≤0.1ppm | Not Detected |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Polydatin?
A1: The standard MOQ is 25KG, support sample orders for formula testing, anti-glycation brightening debugging, barrier repair soothing and anti-aging formula trial production, and support customized polydatin content specifications for mass production.
• Q2: What is the core formula positioning of Polydatin?
A2: It is a high-end high-stability plant-derived dual-effect anti-glycation & anti-oxidation active integrating brightening, soothing repair and light anti-aging, solving the industry pain points of ordinary resveratrol such as poor water solubility, unstable activity and single efficacy. It focuses on improving glycation sallowness, oxidative dullness, sensitive barrier fragility and light aging problems, being a high-value differentiated core raw material for high-end anti-yellowing brightening and anti-aging repair formulas.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional anti-glycation anti-yellowing: 0.5%–2.0%; High-efficiency anti-oxidation brightening: 0.3%–1.5%; Barrier repair & soothing stabilization: 0.8%–2.0%; Light anti-aging maintenance: 0.5%–1.5%, adjustable according to product efficacy positioning and formula system.
• Q4: What are the core advantages compared with ordinary resveratrol?
A4: Ordinary resveratrol has poor water solubility, is easy to decompose and deactivate at high temperature, and only has single antioxidant effect without targeted anti-glycation ability. Polydatin retains the antioxidant activity of resveratrol, and has excellent water solubility, ultra-high light and thermal stability and exclusive anti-glycation efficacy, with dual anti-aging mechanism of anti-oxidation + anti-glycation, multi-effect integration, stronger formula stability and higher product added value.
• Q5: What raw materials is it suitable for compounding?
A5: It is highly compatible with centella hydroxycinnamic acid, morin, dandelion flavonoid, ginkgolide, bamboo leaf flavonoids and trametes versicolor polysaccharide. The compound system can superpose anti-glycation brightening, anti-oxidation anti-aging, barrier repair and soothing efficacy, realizing full closed-loop care for yellow dull skin, sensitive fragile skin and light aging skin.
• Q6: What are the formula usage notes?
A6: Off-white fine powder with excellent water solubility, directly soluble in water phase for feeding; ultra-high light and thermal stability, stable activity in high-temperature batching and long-term light storage, not easy to oxidize and discolor; dissolved in clear and transparent state without affecting finished product high-grade texture and color; suitable for all water-phase, oil-phase and emulsified brightening, repair and anti-aging functional formulas.
• Q7: Can it provide stable supply and professional technical support?
A7: Strictly control core indicators such as polydatin content, moisture content, heavy metals and microorganisms to ensure stable batch consistency. Support long-term bulk order supply, and provide one-stop professional services including anti-glycation brightening formula optimization, barrier repair anti-aging formula upgrading, multi-active compound debugging and after-sales technical guidance.
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